Intracranial pressure and volume wave monitoring system

The project DynICP is focused on developing an advanced, portable prototype of non-invasive intracranial dynamic pressure (ICP) diagnosing and monitoring device which could be utilized at hospitals. Comparing with currently available ICP solutions that requires perforation of cranium (i.e. drilling a hole to skull) and the results would be available after an hour; nICP enables to get the results during ten minutes.

The main objectives of DynICP project was to create innovative technology and methodology of non-invasive monitoring of pulse waves in the way which provides the same diagnostic information as the invasively recorded amplitude of ICP pulse waves. Such objective has been achieved using normalization of non-invasively recorded volumetric pulse waves. Prospective preliminary clinical studies in two independent centres on two different groups of patients were able to preliminary confirm that an innovative DynICP approach is correct and that the objectives are achieved quantitatively analyzing the shape of non-invasively recorded and normalized pulse waves.



ICP(t) pulse waves (dynamic ICP) can be recorded and monitored with better accuracy and precision comparing with mean ICP value. Diagnostic value of ICP pulse waves’ and shape (including ratios of pulse waves’ peaks P1, P2 and P3) is confirmed by many studies. Strong correlation of AUC with the amplitudes of ICP(t) pulse wave peaks confirms a diagnostic value of non-invasive DynICP device.

EII’s main role in the project has been:

  • Coordinating the project,
  • Developing mathematical and signal processing algorithms and software development in order to estimate nICP waveforms from TOF and ABP input signals,
  • Integration of the system.